75+ Vacation Rentals & Holiday Homes in Santee |
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Santee Accommodations - Hotels & Rentals

About Santee Vacation Rentals

Discover More than 75 Incredible Getaway Rentals Available in Santee. Choose from a Wide Selection of Villas, Hotels, and Other Rental Options. Explore Luxury Amenities at Affordable Prices, Creating the Ideal Base for Your Next Vacation. Plan Your Perfect Escape with Online Reservations and Uncover Fantastic Stays in Santee.

Online Reservations Offers Numerous Last-Minute Deals on Villas, Hotels, and Rentals, Both Near You and Across the Globe. Whether You Need Accommodation for a Group or an Event, Be it a Hotel or Vacation Rental (Including Cabins and Private Luxury Villas), We're Here to Assist. With Online Reservations in Santee, You Can Easily Compare Options from Multiple Suppliers with a Single Click to Find the Perfect Price Point, Amenities, and Style of Stay That Suit Your Needs. Looking for Group Deals, Properties with Private Pools, Hot Tubs, Pet-Friendly Options, or Spacious Master Suite Bedrooms with Open-Air Showers? You Can Find It All in the Online Reservations Vacation Rentals, Resorts, and Airbnb-Style Properties in Santee. The Average Size of Places to Stay Near Santee is 1285.14 ft², with Prices Averaging US $439 per Night.

Let Online Reservations Help You Discover the Ideal Holiday Rental to Create Lifelong Travel Memories in Santee. Our Listed Prices Are Often Discounted Compared to Rack Rates. Simply Search for Your Destination and Secure the Perfect Place to Stay Today.

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Top Hotels & Vacation Rentals in Santee

Type Count
Vacation Homes 40
Holiday Apartments 2
Cottages 1

Use these Quick Filters to Find a Vacation Rental in Santee

★ Pro Tip: Online Reservations is a vacation rental website specializing in cottages, lake houses, and exclusive summer home rentals. We curate a vast selection of incredible properties from trusted suppliers, allowing you to compare prices and locations to find the perfect fit for your getaway. Create lasting memories in Santee with Online Reservations.

Weather in Santee, NE

View the weather forecast for Santee before booking your Santee Vacation Rentals to confirm your best time to go.

December - February
High 60°F       Low 26°F
March - May
High 77°F       Low 40°F
June - August
High 91°F       Low 64°F
September - November
High 84°F       Low 38°F

Activities SanteeGuest Reviews Local Attractions

A Large Selection of Hotels and Vacation Rentals from Around the World SanteeGuest Reviews Discover Exciting Activities and Must-Visit Destinations for Your Upcoming Journey


Niobrara State Park
Lewis and Clark Lake
Lewis and Clark Recreation Area
St. Michael's Hospital Avera

Frequently Asked Questions About Santee?

What are the top hotels, lake houses & vacation rentals in Santee?

We provide an array of great vacation destinations in Santee. If you are looking to stay in or around the Santee area, make sure to browse our options to find a premium rental location in a top vacation destination. Whether it is a few nights, a week, or more, we've got the luxury stays that rank among the Top Vacation Rentals in Santee:

Which hotel, lake house, or vacation rental in Santee is best for families?

Searching for a family-friendly getaway in Santee? We've got you covered. Check out one of these luxurious getaways that are highly-rated and perfect fits for families of all sizes.

How many hotels, resorts, or rentals are available in Santee?

Online Reservations™ offers a consistent supply of new options, combined with established great stays in top areas. Currently, the number of properties listed by Online Reservations™ in 2025 is over 75 in the Santee area, and that number rises every day. By combining listings from multiple websites and travel providers, Online Reservations™ can provide you with a diverse amount of choices of the best luxury stays in Santee.


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