337+ Vacation Rentals & Holiday Homes in Los Santos |
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Los Santos Accommodations - Hotels & Rentals

About Los Santos Vacation Rentals

Discover More than 337 Incredible Getaway Rentals Available in Los Santos. Choose from a Wide Selection of Villas, Hotels, and Other Rental Options. Explore Luxury Amenities at Affordable Prices, Creating the Ideal Base for Your Next Vacation. Plan Your Perfect Escape with Online Reservations and Uncover Fantastic Stays in Los Santos.

Online Reservations Offers Numerous Last-Minute Deals on Villas, Hotels, and Rentals, Both Near You and Across the Globe. Whether You Need Accommodation for a Group or an Event, Be it a Hotel or Vacation Rental (Including Cabins and Private Luxury Villas), We're Here to Assist. With Online Reservations in Los Santos, You Can Easily Compare Options from Multiple Suppliers with a Single Click to Find the Perfect Price Point, Amenities, and Style of Stay That Suit Your Needs. Looking for Group Deals, Properties with Private Pools, Hot Tubs, Pet-Friendly Options, or Spacious Master Suite Bedrooms with Open-Air Showers? You Can Find It All in the Online Reservations Vacation Rentals, Resorts, and Airbnb-Style Properties in Los Santos. The Average Size of Places to Stay Near Los Santos is 731.99 ft², with Prices Averaging US $258 per Night.

Let Online Reservations Help You Discover the Ideal Holiday Rental to Create Lifelong Travel Memories in Los Santos. Our Listed Prices Are Often Discounted Compared to Rack Rates. Simply Search for Your Destination and Secure the Perfect Place to Stay Today.

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Top Hotels & Vacation Rentals in Los Santos

Type Count
Vacation Homes 102
Holiday Apartments 73
Villas 69
Cottages 1

Use these Quick Filters to Find a Vacation Rental in Los Santos

★ Pro Tip: Online Reservations is a vacation rental website specializing in cottages, lake houses, and exclusive summer home rentals. We curate a vast selection of incredible properties from trusted suppliers, allowing you to compare prices and locations to find the perfect fit for your getaway. Create lasting memories in Los Santos with Online Reservations.

Weather in Los Santos, PA

View the weather forecast for Los Santos before booking your Los Santos Vacation Rentals to confirm your best time to go.

December - February
High 91°F       Low 72°F
March - May
High 91°F       Low 73°F
June - August
High 90°F       Low 73°F
September - November
High 89°F       Low 74°F

Activities Los SantosGuest Reviews Local Attractions

A Large Selection of Hotels and Vacation Rentals from Around the World Los SantosGuest Reviews Discover Exciting Activities and Must-Visit Destinations for Your Upcoming Journey


Venao Beach
El Uverito Beach
Iguana Island National Park
Los Destiladeros Beach
Playa El Arenal
Belisario Porras Park
Playa Las Comadres
Playa El Toro
Playa El Rompio
Los Buzos Beach
Iglesia Santa Librada
Cerro La Teta
Isla de Canas
Museo de la Nacionalidad
Peninsula de Azuero
ShokoGi Panama
Museo Manuel F Zarate
Guanico Abajo Beach
Refugio de Vida Silvestre Isla Iguana
Museo Belisario Porras
Church of St. Athanasius
Academy of Customs & Traditions Gabriel Villarreal

Find Hotels & Vacation Rentals in these Cities and Neighborhoods


Peninsula de Azuero 358 Properties
Isla Canas 178 Properties
Las Escobas del Venado 130 Properties
Venao Beach 130 Properties
Punta Mala 71 Properties
Canas 53 Properties
Pedasi 44 Properties
La Villa de los Santos 35 Properties
El Rompio 28 Properties
Las Tablas 25 Properties
Cambutal 24 Properties
Guanico Abajo 24 Properties

Frequently Asked Questions About Los Santos?

What are the top hotels, lake houses & vacation rentals in Los Santos?

We provide an array of great vacation destinations in Los Santos. If you are looking to stay in or around the Los Santos area, make sure to browse our options to find a premium rental location in a top vacation destination. Whether it is a few nights, a week, or more, we've got the luxury stays that rank among the Top Vacation Rentals in Los Santos:

How many Hotels & Vacation Rentals have private pools in Los Santos?

We have 28 Hotels & Vacation Rentals featuring a private pool in and near Los Santos. Some of the best destinations to stay that feature or have access to a swimming pool are:

Which hotel, lake house, or vacation rental in Los Santos is best for families?

Searching for a family-friendly getaway in Los Santos? We've got you covered. Check out one of these luxurious getaways that are highly-rated and perfect fits for families of all sizes.

How many hotels, resorts, or rentals are available in Los Santos?

Online Reservations™ offers a consistent supply of new options, combined with established great stays in top areas. Currently, the number of properties listed by Online Reservations™ in 2025 is over 337 in the Los Santos area, and that number rises every day. By combining listings from multiple websites and travel providers, Online Reservations™ can provide you with a diverse amount of choices of the best luxury stays in Los Santos.


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