977+ Vacation Rentals & Holiday Homes in Matlacha Isles-Matlacha Shores |
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Matlacha Isles-Matlacha Shores Accommodations - Hotels & Rentals

About Matlacha Isles-Matlacha Shores Vacation Rentals

Discover More than 977 Incredible Getaway Rentals Available in Matlacha Isles-Matlacha Shores. Choose from a Wide Selection of Villas, Hotels, and Other Rental Options. Explore Luxury Amenities at Affordable Prices, Creating the Ideal Base for Your Next Vacation. Plan Your Perfect Escape with Online Reservations and Uncover Fantastic Stays in Matlacha Isles-Matlacha Shores.

Online Reservations Offers Numerous Last-Minute Deals on Villas, Hotels, and Rentals, Both Near You and Across the Globe. Whether You Need Accommodation for a Group or an Event, Be it a Hotel or Vacation Rental (Including Cabins and Private Luxury Villas), We're Here to Assist. With Online Reservations in Matlacha Isles-Matlacha Shores, You Can Easily Compare Options from Multiple Suppliers with a Single Click to Find the Perfect Price Point, Amenities, and Style of Stay That Suit Your Needs. Looking for Group Deals, Properties with Private Pools, Hot Tubs, Pet-Friendly Options, or Spacious Master Suite Bedrooms with Open-Air Showers? You Can Find It All in the Online Reservations Vacation Rentals, Resorts, and Airbnb-Style Properties in Matlacha Isles-Matlacha Shores. The Average Size of Places to Stay Near Matlacha Isles-Matlacha Shores is 1391.15 ft², with Prices Averaging $266 per Night.

Let Online Reservations Help You Discover the Ideal Holiday Rental to Create Lifelong Travel Memories in Matlacha Isles-Matlacha Shores. Our Listed Prices Are Often Discounted Compared to Rack Rates. Simply Search for Your Destination and Secure the Perfect Place to Stay Today.

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Top Hotels & Vacation Rentals in Matlacha Isles-Matlacha Shores

Type Count
Vacation Homes 730
Villas 144
Holiday Apartments 49
Cottages 17

Use these Quick Filters to Find a Vacation Rental in Matlacha Isles-Matlacha Shores

★ Pro Tip: Online Reservations is a vacation rental website specializing in cottages, lake houses, and exclusive summer home rentals. We curate a vast selection of incredible properties from trusted suppliers, allowing you to compare prices and locations to find the perfect fit for your getaway. Create lasting memories in Matlacha Isles-Matlacha Shores with Online Reservations.

Weather in Matlacha Isles-Matlacha Shores, FL

View the weather forecast for Matlacha Isles-Matlacha Shores before booking your Matlacha Isles-Matlacha Shores Vacation Rentals to confirm your best time to go.

December - February
High 60°F       Low 26°F
March - May
High 77°F       Low 40°F
June - August
High 91°F       Low 64°F
September - November
High 84°F       Low 38°F

Activities Matlacha Isles-Matlacha ShoresGuest Reviews Local Attractions

A Large Selection of Hotels and Vacation Rentals from Around the World Matlacha Isles-Matlacha ShoresGuest Reviews Discover Exciting Activities and Must-Visit Destinations for Your Upcoming Journey


Griffen American Center for Haitian Art
Captiva Beach
Sanibel Island Southern Beach
Times Square
Fishing Pier Fort Myers Beach
Bowman's Beach
Boca Grande Beach
Edison and Ford Winter Estates
Manatee Park
Sanibel Island Lighthouse
Bell Tower Shops
Fort Myers Country Club
CenturyLink Sports Complex
Sanibel Island Golf Club
Gasparilla Island State Park
San Carlos Island
Bunche Beach
Centennial Park
Sun Splash Water Park
Florida Southwestern State College

Find Hotels & Vacation Rentals in these Cities and Neighborhoods


Griffen American Center for Haitian Art 624 Properties

Frequently Asked Questions About Matlacha Isles-Matlacha Shores?

What are the top hotels, lake houses & vacation rentals in Matlacha Isles-Matlacha Shores?

We provide an array of great vacation destinations in Matlacha Isles-Matlacha Shores. If you are looking to stay in or around the Matlacha Isles-Matlacha Shores area, make sure to browse our options to find a premium rental location in a top vacation destination. Whether it is a few nights, a week, or more, we've got the luxury stays that rank among the Top Vacation Rentals in Matlacha Isles-Matlacha Shores:

How many Hotels & Vacation Rentals have private pools in Matlacha Isles-Matlacha Shores?

We have 396 Hotels & Vacation Rentals featuring a private pool in and near Matlacha Isles-Matlacha Shores. Some of the best destinations to stay that feature or have access to a swimming pool are:

Which hotel, lake house, or vacation rental in Matlacha Isles-Matlacha Shores is best for families?

Searching for a family-friendly getaway in Matlacha Isles-Matlacha Shores? We've got you covered. Check out one of these luxurious getaways that are highly-rated and perfect fits for families of all sizes.

How many hotels, resorts, or rentals are available in Matlacha Isles-Matlacha Shores?

Online Reservations™ offers a consistent supply of new options, combined with established great stays in top areas. Currently, the number of properties listed by Online Reservations™ in 2025 is over 977 in the Matlacha Isles-Matlacha Shores area, and that number rises every day. By combining listings from multiple websites and travel providers, Online Reservations™ can provide you with a diverse amount of choices of the best luxury stays in Matlacha Isles-Matlacha Shores.

Nearby Neighborhood (1) 
Neighborhood Property Count
Burnt Store Vacation Rentals in Fort Myers, Florida 407

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